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Histone lactylation (Kla) describes a posttranslational modification (PTM) mechanism wherein lactate induces epigenetic modification, i.e., the addition of a lactyl group to the ε-amino group of a lysine residue of histone, which directly modulates gene transcription [92]

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Infection rates are high among rural communities engaged in water-related agricultural activities, as well as among women and children who use contaminated water for household chores [9]