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[106] found Kiss1 or Gpr54 promoter-driven β-galactosidase activity in the testis as well as in the hypothalamus of knock-in mice carrying targeted mutations in Kiss1 or Gpr54 loci with a LacZ insertion

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Moreover, H 2 S induces sulfhydrylation of Kelch-like ECH-associated protein 1 (Keap1) at Cys151, promotes its association with (NF-E2)-related factor 2 (Nrf2), and increases the expression of Nrf2-associated antioxidant genes in vivo and in vitro, thereby improving liver function and reducing liver fibrosis