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Understanding your genetic predisposition in GLP-1 pathways can support a more informed conversation with your provider about whether oral or injectable B12 is appropriate for your individual risk profile and whether more frequent baseline and follow-up testing is warranted before starting semaglutide

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Vitamin B12 is absorbed in our ileum so those with ileocolitis (Crohns in the ileum) and anyone who has had ileal resection is at greater risk of B12 deficiency