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Additionally, NAC may directly modulate inflammatory signaling pathways, including nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs), leading to the suppression of pro-inflammatory cytokines and chemokines

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The lack of HrpA/HrpB TPS in the gonococcus would explain why the gonococcus remains predominantly confined within a vacuole during cellular infection, unlike the meningococcus, which is able to escape, and why the meningococcus, after reaching the cytosol, induces pyroptotic pathways during cellular infection, a phenomenon not described for the gonococcus