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However, it is possible that the combined effect of ALDH1A1 and ALDH2 polymorphisms may lead to considerable variability in alcohol metabolism, affecting tolerance, dependence, and alcohol-related diseases across individuals and populations
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Per BNF and BSH guidance: For confirmed deficiency without neurological involvement: 1 mg IM on alternate days for two weeks, then 1 mg every two to three months for maintenance
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