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Skin Repair Pathways — MMP/TIMP, Collagen & Elastin (PMC, 2015) A focused review of GHK as a modulator of multiple skin regeneration pathways published in PMC confirmed that GHK-Cu stimulates both synthesis and breakdown of collagen and glycosaminoglycans, and modulates the activity of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs)

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[DOI] [PubMed] [Google Scholar] 14.Pountos I, Georgouli T, Kontakis G, Giannoudis PV