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Cell viability assays To evaluate cell viability, 143B and K7M2 cells were seeded in 96-well plates at a density of 5 × 10 3 cells per well and cultured for 24 h

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Over time, the circuit reasserts itself, hunger signals return at lower body weights than they would have appeared at without medication, and the patient finds that maintaining the deficit takes more deliberate effort than it did in months one through six