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10.3389/fpsyt.2022.893309 73 ZhengG.YeB.ZhengY.XiongZ.XiaR.QiuP.et al
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Skin + Gut:Skin + Gut
5.1.2 Enhancement of gut and blood–brain barrier integrity Recent studies have shown that a vicious cycle of inflammation and oxidative stress is created at the renal level by the influx of uremic toxins and urea into the gastrointestinal lumen via the enterohepatic cycle, which exerts a selective pressure that encourages the excessive growth of bacterial species that produce urease, uricase, indole, and p-cresol-forming enzymes with a reduction in SCFAs-producing species (Vaziri et al., 2013
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