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There are three main ways: Methylmalonic acid (MMA) MMA is one of the most useful markers for detecting B12 deficiency, because B12 helps convert methylmalonyl-CoA—one of the forms of MMA—into succinyl-CoA
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It beats oral supplements hands down, delivering 100% absorption while pills only manage about 1.3% of a 1,000 mcg dose due to digestive hurdles
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