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Arsenic toxicity cripples cellular respiration by targeting the lipoic acid cofactor of key dehydrogenase complexes. Lipoic acid operates as a swinging arm in the E2 subunits of pyruvate dehydrogenase and α‑ketoglutarate dehydrogenase
in comparison, GSH showed no protective effect, suggesting that SAG may be uniquely suited to support the body’s response to viral challenge
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